Establishment of a bio-chip technology for early diagnosis and treatment of cancer

Tadashi Matsunaga, Vice-President, Tokyo Agricultural University
(FY2010-2012)

Using bio-magnetic beads, biochip technology and cell integrated microchips, we aim to research, develop and commercialize tools for cancer treatment and early diagnosis.

FY2010 results

1. In the development of magnetic beads expressing MHC, we succeeded in developing MHC magnetic beads that significantly increased the amount of class I and class II MHC per particle.
2. In the development of cell integrated microchips, when using model tumor cells, we were able to obtain a detection efficiency of over 96% under conditions of 10-100 tumor cells per 1 mL of blood. In addition, improvement of the microchips has been shown to significantly reduce residual leukocytes.